Archive for September, 2008
Our Science, Your Secret AgeLoc
Why is it that when it comes to aging and our appearance, time appears to secretly stand still for some? In a revolutionary skin care breakthrough, Nu Skin and Purdue University have unlocked the science behind the secret. Research shows our personal levels of a newly discovered internal aging accelerator can make us look older or younger than our biological age.
Now Nu Skin has found a key to helping control your skin’s destiny with Nu Skin Galvanic Facial Gels featuring ageLOC—a powerful aging antidote that helps decrease signs of visible aging. Only Nu Skin gives you control of your skin’s future and helps you improve your appearance faster. So let our science be your secret and make your age a mystery.
arNOX Information from Stanford Clinical Bulletin

Although the skin care industry has made some significant progress toward the correction and prevention of the visible signs of aging, there are still many unknown factors regarding why we age—and why we all seem to age differently.
The effects of the sun and the environment are fairly well understood and highly effective sunscreens exist to help us avoid the aggressive aging effects of ongoing exposure. Less understood are the biological or intrinsic processes that affect our appearance over time.
Recently, scientists at Purdue University in collaboration with Nu Skin Research and Development, have discovered a new and potentially significant internal source of aging—an enzyme called arNOX. Present on the surface of our cells, this enzyme is capable of generating skin damaging free radicals in the epidermis around the clock.
Mostly inactive in our youth, activity levels of arNOX increase as we age and vary by individual.
Anti Aging Breakthrough Identified By Nu Skin

New research funded by Nu Skin Enterprises on internal causes of aging has identified a previously unknown source of superoxide free radicals. Free radicals from external triggers, such as sun exposure and cigarette smoke, have long been known to damage skin cells and components of the skin’s extracellular matrix, including collagen and elastin.
Scientists from Nu Skin Enterprises and Purdue University report their novel research findings on age-related NADH oxidase (arNOX) this week in Kyoto, Japan, at International Investigative Dermatology 2008 (IID2008), a major scientific venue for the latest information on skin biology.
The scientists present compelling evidence that arNOX, an enzyme associated with cell membranes, is present and active on skin cells. Significantly, arNOX activity increases during the “aging” years of about 45-70. “Identifying skin-associated arNOX and its increasing activity with age is a breakthrough discovery in understanding skin aging,” said Zoe Diana Draelos, MD, primary investigator with Dermatology Consulting Services, member of the Nu Skin Scientific Advisory Board and one of the study authors. “Currently, most dermatological research focuses on correcting skin damage after it occurs.
Identifying an internal source of free radicals in skin, and advancing an understanding of how and why they are generated, adds to our ability to address fundamental mechanisms that may combine with external sources to lead to accelerated skin aging.” “Evidence of arNOX in the skin provides further insights into potentially revolutionary therapies for skin care, particularly because its activity correlates with the ages when people begin to see their skin lose its elasticity and firmness, and notice more discoloration and lines and wrinkles,” remarked Helen Knaggs, PhD, vice president of Nu Skin global research and development. “If we can develop innovative ways to inhibit arNOX activity and prevent the production of free radicals in the first place, then we can address both sides of the equation — correcting free radical damage from external sources, while at the same time preventing free radical production from internal sources.”
This remarkable discovery will lead the way for a revolutionary new skin care line called AgeLoc.
Further References: National Institutes Of Health
The AgeLoc breakthrough







































